Everyone Healthy Library
Fatty Liver
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Linked signs and symptoms
2Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
24Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
3Lifestyle changes
6Alternative and complementary therapies
5Alternative medicine
5- Celandine (Ukrain, Chelidonium Majus)Weakly Against(Very Low Evidence)
- CiticolineEvidence: 2
- Indian Snakeroot (Rauvolfia, Rawolfia Serpentina)No Recommendation(Very Low Evidence)
- Licorice (Glycyrrhiza Glabra, Gan Cao)No Recommendation(Very Low Evidence)
- Tumeric (Curcuma longa)No Recommendation(Very Low Evidence)
Alternative therapies
1Amino acids
1Linked diagnostic tests and investigations
42These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Acid Phosphatase Concentration
- Activated Coagulation Time (ACT)
- Activated Partial Thromboplastin Time (APTT)
- Alpha-1 Antitrypsin (AAT) Concentration
- Antithrombin 111 (AT-111) Activity Test
- Aspartate Aminotransferase (AST) Concentration
- Blood Urea Nitrogen Tests
- Blood Uric Acid Concentration Test
- Coagulation Factor Assay (Blood Clotting Factors)
- Creatine Kinase Concentration
- D-Dimer Blood Test
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrin Monomers Test
- Fibrinogen Concentration test
- Folic Acid (Folate) Concentration
- Gamma-Glutamyltransferase (GGT) Concentration
- Glucose Tolerance Test (GTT, OGTT, 120 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 160 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 30 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, 60 Minutes After Glucose Load)
- Glucose Tolerance Test (GTT, OGTT, Fasting Glucose)
- Glucose Tolerance Test for Gestational Diabetes (1 Hour After Glucose Load)
- Glucose Tolerance Test for Gestational Diabetes (Fasting Glucose Value)
- Glucose, Blood (Post Prandiol Blood Glucose Test, 2 Hour Post Meal Blood Glucose)
- haptoglobin (Hp) concentration
- HPV DNA Test
- Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Lactate Dehydrogenase Concentration
- Lactic Acid Concentration
- lipase concentration
- Low Density Lipoprotein (LDL) Concentration
- Mean Corpuscular Volume (MCV)
- Osmolality, Blood (Serum Osmolality)
- Phenylketonuria Test
- Potassium Concentration (K, Blood)
- Protein Electrophoresis (Blood, Serum Protein)
- Prothrombin Time (PT)
- scratch-N-Sniff Odor Tests
- Thrombin Time
- Triiodothyronine (Free T3) Concentration
- Urine Crystal Concentration
- Urine Sodium Quantitative (24hr)
Biological and test markers
40This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
22- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic tests1Acid Phosphatase Concentration
- Aspartate Aminotransferase (AST)Reference range exampleAdult ( > 16y), Female: 10–25 units/L; Adult ( > 16y), Male: 10–35 units/LLinked diagnostic tests1Aspartate Aminotransferase (AST) Concentration
- Calcium Oxalate Crystals (Urine)Reference range exampleAll: 0–1 Not PresentLinked diagnostic tests1Urine Crystal Concentration
- Coagulation Bleeding TimeReference range exampleAdult ( > 16y): 65–110 secondsLinked diagnostic tests1Activated Coagulation Time (ACT)
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic tests1D-Dimer Blood Test
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic tests1Fibrin Monomers Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic tests1Fibrin Degradation Products (FDPs, Fibrin Split Products
- Gamma Globulin (Blood, Serum)Reference range exampleAll: 0.8–1.7 gm/dLLinked diagnostic tests1Protein Electrophoresis (Blood, Serum Protein)
- Gamma-Glutamyltransferase (GGT)Reference range exampleAdult ( > 16y), Female: 6–30 units/L; Adult ( > 16y), Male: 6–38 units/LLinked diagnostic tests1Gamma-Glutamyltransferase (GGT) Concentration
- Human Placental Lactogen (HPL, Pregnancy Weaks 25 to 30)Reference range exampleAdult ( > 16y), Female: 2,300–6,100 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 31 to 35)Reference range exampleAdult ( > 16y), Female: 3,800–8,800 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 36 to 40)Reference range exampleAdult ( > 16y), Female: 4,900–8,600 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (HPL, Pregnancy Weaks 5 to 25)Reference range exampleAdult ( > 16y), Female: 0–4,500 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Lactate Dehydrogenase (LDH)Reference range exampleInfant (0 - 1y): 120–250 units/L; Adult ( > 16y): 100–200 units/LLinked diagnostic tests1Lactate Dehydrogenase Concentration
- Lactic Acid (Venous Blood)Reference range exampleAll: 0.5–2.2 mEq/LLinked diagnostic tests1Lactic Acid Concentration
- LipaseReference range exampleAdult ( > 16y): 10–140 units/LLinked diagnostic tests1lipase concentration
- Low Density Lipoprotein (LDL)Reference range exampleAdult ( > 16y): 0–125 mg/dL; 6y - 16y: 0–100 mg/dLLinked diagnostic tests1Low Density Lipoprotein (LDL) Concentration
- Osmolality, Blood (Serum Osmolality)Reference range exampleChild (0 - 16y): 274–290 mOsm/kg; Birth - 2wks: 265–285 mOsm/kgLinked diagnostic tests1Osmolality, Blood (Serum Osmolality)
- PhenylalanineReference range exampleAdult ( > 16y): 0–16 mg/24hrs; Child (5 - 12y): 4–16.5 mg/24hrsLinked diagnostic tests1Phenylketonuria Test
- Plasma thromboplastin antecedentReference range exampleAdult ( > 16y): 20–35 secondsLinked diagnostic tests1Activated Partial Thromboplastin Time (APTT)
- Red Blood Cell (RBC) VolumeReference range example76–100 fLLinked diagnostic tests1Mean Corpuscular Volume (MCV)
- Thrombin TimeReference range exampleAdult ( > 16y): 10–20 secondsLinked diagnostic tests1Thrombin Time
Often decreased
18- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic tests1Alpha-1 Antitrypsin (AAT) Concentration
- Antithrombin 111 (AT-111)Reference range exampleAdult ( > 16y): 90–110 %Linked diagnostic tests1Antithrombin 111 (AT-111) Activity Test
- Blood Urea NitrogenReference range exampleAdult ( > 16y): 6–18 mg/dL; Child (< 10y): 5–15 mg/dLLinked diagnostic tests1Blood Urea Nitrogen Tests
- Creatine Kinase (CK)Reference range exampleAdult ( > 16y), Female: 35–150 units/L; Adult ( > 16y), Male: 40–170 units/LLinked diagnostic tests1Creatine Kinase Concentration
- Factor II (Prothrombin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 80–120 %; Adult ( > 16y): 80–120 %Linked diagnostic tests3Coagulation Factor Assay (Blood CLotting Factors, Coagulation Factor Assay (Blood Clotting Factors)
- Factor IX (Christmas Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 60–140 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- Factor V (Labile Factor, Proaccelerin, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- Factor X (Stuart Prower Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 45–155 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- Factor XI (Plasma Thromboplastin Antecedent, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 65–135 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- Factor XII (Hageman Factor, Percentage of Normal Value)Reference range exampleAdult ( > 16y): 50–150 %Linked diagnostic tests1Coagulation Factor Assay (Blood Clotting Factors)
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic tests1Fibrinogen Concentration test
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic tests1Folic Acid (Folate) Concentration
- Glucose (Blood)Reference range exampleInfant (0 - 1y): 3–6.1 mmol/L; Adult ( > 16y): 0–6.1 mmol/LLinked diagnostic tests11fasting Blood Glucose Test, Glucose Tolerance Test (GTT
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic tests1haptoglobin (Hp) concentration
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic tests1Potassium Concentration (K, Blood)
- Triiodothyronine (Free T3)Reference range example2.7–4.9 pg/mLLinked diagnostic tests1Triiodothyronine (Free T3) Concentration
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic tests1Blood Uric Acid Concentration Test
- Urine SodiumReference range exampleChild (0 - 16y): 41–115 mmol/day; Adult ( > 16y): 40–220 mmol/dayLinked diagnostic tests1Urine Sodium Quantitative (24hr)
Other associated markers
0No markers in this group.
Introduction / full article
Fatty Liver
Fatty liver
This is the effect of the accumulation of different types of fats in the liver. There should be balance between the fatty acids that enter the liver with the amount that is excreted out but this cycle is not followed when there is Fatty Liver. The most common cause of Fatty Liver is excessive alcohol intake. But it should be taken note of that even people who do not drink alcohol are also at risk in having Fatty Liver especially those with Diabetes and are Obese. Symptoms are fatigue, excessive weight loss, headache, and inability to concentrate and make sound judgment.
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Turmeric [1, 10, 11, 12, 13, 14, 15]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that turmeric can help in the treatment of liver disease. More research is needed.)
Grade of Evidence: very low quality of evidence
Licorice (Glcyrhiz Gaba) [1, 6, 7, 8, 9]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present. Licorice has been shown to have potentially harmful side effects in people with high blood pressure, liver or kidney diseases)
Recommendation: No recommendation (There is insufficient evidence to support claims that licorice helps treat some symptoms of a fatty liver. More research is needed)
Grade of Evidence: very low quality of evidence
Indian Snakeroot (Rauvolfia, Rawolfia Serpentina) [1, 4, 5]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that Indian Snakeroot helps to treat fatty livers in any way)
Grade of Evidence: very low quality of evidence
Celandine (Ukrain, Chelidonium Majus) [1, 2, 3]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: weakly against (There is insufficient evidence that Celandine helps to cure or treat liver fibrosis. In addition, the plant is mildly poisonous to humans. It may cause hepatitis as well as symptoms of pain, nausea, thirst, and fever.)
Grade of Evidence: very low quality of evidence
Neural Therapy:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recomendation (there is insufficient evidence to show that Neural Therapy helps in treating Fatty Liver in any way)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://abchomeopathy.com/r.php/Chel
3. http://www.naturalstandard.com/index-abstract.asp?create-abstract=/monographs/herbssupplements/greatercelandine.asp
4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/indian-snakeroot
5. http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/seven/000092149.htm
6. Winston, David; Steven Maimes (2007). Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Healing Arts Press.
7. http://www.ncbi.nlm.nih.gov/pubmed/15190039
8. http://nccam.nih.gov/health/licoriceroot/
9. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-licorice.html
10. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/turmeric
11. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-turmeric.html
12. http://nccam.nih.gov/health/turmeric/index.htm
13. http://news.bbc.co.uk/2/hi/health/1668932.stm
14. http://www.mirror.co.uk/news/top-stories/2009/10/28/curry-kills-cancer-cells-and-other-health-benefits-of-the-nations-favourite-dish-115875-21779950/
15. http://clinicaltrials.gov/ct2/results?term=turmeric