Everyone Healthy Library
Giant Cell Tumor of Bone
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
0No linked drugs are listed yet.
Treatments, therapies and supportive options
16Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
4Medical therapy
7- Bone Transplant (Graft)Weakly in Favour(Low Evidence)
- Chemical Heat TherapyWeakly in Favour(Low Evidence)
- ExcisionWeakly in Favour(Low Evidence)
- ImmobilizationWeakly in Favour(Low Evidence)
- Radiation TreatmentWeakly in Favour(Low Evidence)
- ReconstructionWeakly in Favour(Low Evidence)
- Thermal Heat TherapyWeakly in Favour(Low Evidence)
Linked diagnostic tests and investigations
16These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- Alpha-1 Antitrypsin (AAT) Concentration
- Calcium Concentration (Blood, Total)
- Cerebrospinal Fluid Albumin Concentration
- Cerebrospinal Fluid Protein Concentration
- Cerebrospinal Fluid Protein Electrophoresis
- Cerebrospinal Fluid White Cell Differential
- D-Dimer Blood Test
- Fibrin Degradation Products (FDPs, Fibrin Split Products, FSPs, Fibrin Breakdown Products, Fbps)
- Fibrin Monomers Test
- Neutrophil Absolute Count
- Plasminogen Activity
- Platelet Count
- Red Blood Cell (RBC) Count
- Thyroxine (Total T4) Concentration
- Triiodothyronine (Total T3) Concentration
- Urine Chloride Concentration
Biological and test markers
15This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
11- Albumin (Cerebrospinal Fluid, CSF)Reference range exampleAll: 10–35 mg/dL; All: 56–76 %Linked diagnostic tests2Cerebrospinal Fluid Albumin Concentration, Cerebrospinal Fluid Protein Electrophoresis
- Alpha-1 Antintrypsin (AAT)Reference range exampleAdult ( > 16y): 90–215 mg/dLLinked diagnostic tests1Alpha-1 Antitrypsin (AAT) Concentration
- Calcium (Blood, Total)Reference range exampleAdult ( > 16y): 8.5–10.4 mg/dL; Birth - 2wks: 7.6–10.3 mg/dLLinked diagnostic tests1Calcium Concentration (Blood, Total)
- Cerebrospinal Fluid Neutrophil DifferentialReference range exampleAll: 0–5 %Linked diagnostic tests1Cerebrospinal Fluid White Cell Differential
- Cerebrospinal Fluid Total ProteinReference range exampleAdult ( > 16y): 15–45 mg/dL; Child (< 10y): 15–70 mg/dLLinked diagnostic tests1Cerebrospinal Fluid Protein Concentration
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic tests1D-Dimer Blood Test
- Fibrin MonomersReference range example0–10,000 µg/LLinked diagnostic tests1Fibrin Monomers Test
- Fibrin Split ProductsReference range exampleAll: 0–1 mg/dLLinked diagnostic tests1Fibrin Degradation Products (FDPs, Fibrin Split Products
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic tests1Platelet Count
- Segmented NeutrophilsReference range exampleAdult ( > 16y): 50–62 %; Adult ( > 16y): 2,500–8,000 mm3Linked diagnostic tests2Differential White Blood Cell Count Tests, Neutrophil Absolute Count
- Urine ChlorideReference range exampleInfant (0 - 1y): 2–10 mmol/day; Child (0 - 16y): 15–14 mmol/dayLinked diagnostic tests1Urine Chloride Concentration
Often decreased
4- PlasminogenReference range exampleAdult ( > 16y), Female: 65–153 %; Adult ( > 16y), Male: 70–120 %Linked diagnostic tests1Plasminogen Activity
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic tests1Red Blood Cell (RBC) Count
- Thyroxine (Total T4)Reference range exampleAdult ( > 16y), Female: 6–12 µg/dL; Adult ( > 16y), Male: 5–12 µg/dLLinked diagnostic tests1Thyroxine (Total T4) Concentration
- Triiodothyronine (Total T3)Reference range exampleInfant (0 - 1y): 1.1–2.43 ng/mL; Adult ( > 16y): 1–2.1 ng/mLLinked diagnostic tests1Triiodothyronine (Total T3) Concentration
Other associated markers
0No markers in this group.
Introduction / full article
Giant Cell Tumor of Bone
Summary References
Treatments:
1. Balke M, Schremper L, Gebert C, et al. (March 2008). "Giant cell tumor of bone: treatment and outcome of 214 cases". J. Cancer Res. Clin. Oncol. 134 (9): 969. doi:10.1007/s00432-008-0370-x.
2. Mendenhall W, Zlotecki R, Scarborough M, Gibbs C, Mendenhall N (2006). "Giant cell tumor of bone". Am J Clin Oncol 29 (1): 96–9. doi:10.1097/01.coc.0000195089.11620.b7
3. http://www.merck.com/mmpe/sec04/ch044/ch044b.html?qt=giant%20cell%20tumour&alt=sh#sec04-ch044-ch044b-1163
4. http://www.ejbjs.org/cgi/reprint/41/5/895.pdf
5. http://www3.interscience.wiley.com/journal/112668320/abstract?CRETRY=1&SRETRY=0
6. http://www.ejbjs.org/cgi/content/abstract/81/6/811
7. http://www.ejbjs.org/cgi/content/abstract/69/1/106
8. http://www3.interscience.wiley.com/journal/112665380/abstract