Everyone Healthy Library
Neuropathic Pain
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Linked signs and symptoms
10Each sign/symptom opens its own page and links back to related conditions.
Linked drugs / medications
3Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
20Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Surgery
3Medical therapy
5- Microvascular DecompressionWeakly in Favour(Low Evidence)
- Neural Augmentative SurgeryWeakly in Favour(Low Evidence)
- RhizotomyWeakly in Favour(Low Evidence)
- Transcutaneous Electrical Nerve Stimulation (TENS)Weakly in Favour(Low Evidence)
- Transcutaneous Neuromuscular Electrical StimulationNo Recommendation(Low Evidence)
Alternative and complementary therapies
8Alternative medicine
1Vitamins and minerals
1Linked diagnostic tests and investigations
3These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological and test markers
3This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
2Often decreased
1Other associated markers
0No markers in this group.
Introduction / full article
Neuropathic Pain
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Peppermint Oil [1, 11, 12, 13, 14, 15, 16]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that peppermint helps to treat neuropathic pain)
Grade of Evidence: very low quality of evidence
Cannabis (Marijuana, weed, hemp) [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly in favor (Evidence shows that smoking or ingesting cannabis may help in relieving symptoms of pain, although some studies have yielded mixed results)
Grade of Evidence: low quality of evidence
Red Pepper (Capsaicin):
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: strongly in favor (Evidence suggest that red peppers can reduce the degree of neuropathic pain in patients after surgery)
Grade of Evidence: moderate quality of evidence
Transcutaneous Electrical Neuromuscular Stimulation:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is not enough evidence supporting the role of TENS in chronic pain therapy)
Grade of Evidence: low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. http://www.nlm.nih.gov/medlineplus/marijuana.html
3. http://nccam.nih.gov/research/extramural/awards/2004/
4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/marijuana
5. http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms/treatments/complementary--alternative-medicine/marijuana/index.aspx
6. http://www.ncbi.nlm.nih.gov/pubmed/16957511
7. http://www.ncbi.nlm.nih.gov/pubmed/12965981
8. http://www.ncbi.nlm.nih.gov/pubmed/17589370
9. http://mct.aacrjournals.org/content/6/11/2921.long
10. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562334/?tool=pmcentrez
11. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/peppermint
12. http://www.ncbi.nlm.nih.gov/pubmed/17420159
13. http://www.ncbi.nlm.nih.gov/pubmed/19507027
14. http://www.medicine.ox.ac.uk/bandolier/booth/alternat/AT022.html
15. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-peppermint.html
16. http://nccam.nih.gov/health/peppermintoil/index.htm