Everyone Healthy Library
Pain (Chronic)
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Linked signs and symptoms
0No related signs or symptoms are listed yet.
Linked drugs / medications
10Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
43Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
2Alternative and complementary therapies
29- Acupuncture
- Aromatherapy
- Ayurvedic Medicine (Ayurveda)No Recommendation(Very Low Evidence)
- Black Cohosh Plant (Actaea racemosa)No Recommendation(Moderate Evidence)
- Cannabis (Marijuana)Weakly in Favour(Low Evidence)
- Chaparral (Larrea Tridentata Coville)Strongly Against(Low Evidence)
- Creative Art Therapy (Expressive Therapy)No Recommendation(Very Low Evidence)
- Curanderismo
- Humor Therapy
- Hypnosis
- Image Therapy
- Magnetic Therapy
- Massage
- Meditation
- Music Therapy
- Myofascial ReleaseNo Recommendation(Very Low Evidence)
- Native American HealingNo Recommendation(Very Low Evidence)
- Naturopathic MedicineNo Recommendation(Very Low Evidence)
- Neural TherapyNo Recommendation(Very Low Evidence)
- Osteopathy
- Pau Darco (Lapachol, Tabebuia Impetiginosa, Tabebuia Heptaphylla)Strongly Against(Very Low Evidence)
- Polarity Therapy
- Qigong
- Red Pepper (Capsaicin)No Recommendation(Very Low Evidence)
- Reflexology
- Reiki
- Strychnos Nux-Vomica (Maqianzi, Poison Nut)Strongly Against(Very Low Evidence)
- Therapeutic Touch
- Turmeric
Alternative medicine
8- Ayurvedic Medicine (Ayurveda)No Recommendation(Very Low Evidence)
- Chaparral (Larrea Tridentata Coville)Strongly Against(Low Evidence)
- CuranderismoNo Recommendation(Very Low Evidence)
- Naturopathic MedicineNo Recommendation(Very Low Evidence)
- Pau Darco (Lapachol, Tabebuia Impetiginosa, Tabebuia Heptaphylla)Strongly Against(Very Low Evidence)
- Red Pepper (Capsaicin)No Recommendation(Very Low Evidence)
- Strychnos Nux Vomica (Maqianzi, Poison Nut)Strongly Against(Very Low Evidence)
- Tumeric (Curcuma longa)No Recommendation(Very Low Evidence)
Alternative therapies
1Linked diagnostic tests and investigations
2These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
Biological and test markers
2This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
2Often decreased
0No markers in this group.
Other associated markers
0No markers in this group.
Introduction / full article
Pain (Chronic)
Efficacy of Alternative and Other Treatments According to GRADE* Ranking:
Turmeric [1, 18, 19, 20, 21, 22, 23]:
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: No recommendation (There is insufficient evidence to support claims that turmeric can help in the treatment of pain. More research is needed.)
Grade of Evidence: very low quality of evidence
Strychnos Nux-Vomica (Maqianzi, Poison Nut) [1, 15, 16, 17]:
WARNING! This substance is HIGHLY POISONOUS. The seeds contain Strychnine, which may cause convulsions, breathing difficulties and death, even if as little as 5 milligrams is ingested.
Recommendation: Strongly against (There is no evidence in the form of clinical trials which reports the effectiveness of Strychnos Nux-Vomica, because it is highly poisonous to humans, and is not recommended.)
Grade of Evidence: very low quality of evidence
Pau D'Arco (Lapachol, Tabebuia Impetiginosa, Tabebuia Heptaphylla) [1, 14]:
Please note, this treatment has potentially serious side effects. Some of the chemicals in the plant are known to be toxic. High doses are known to cause liver and kidney. Even at low doses, chemicals in the plant may interfere with blood clotting, causing excess bleeding and anaemia. Pau D'Arco should be avoided, especially by pregnant or breastfeeding women.
Recommendation: Strongly against (There is insufficient evidence to support claims that Pau D'arco helps to treat pain. This, combined with its potentially harmful side effects if taken without supervision from a doctor or pharmacist gives enough reason to avoid this treatment.)
Grade of Evidence: very low quality of evidence
Cannabis (Marijuana, weed, hemp) [1, 5, 6, 7, 8, 9, 10, 11, 12, 13]:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: Weakly in favor (Evidence shows that smoking or ingesting cannabis may help in relieving symptoms of pain, although some studies have yielded mixed results)
Grade of Evidence: low quality of evidence
Chaparral (Larrea Tridentata Coville [1, 2, 3, 4]:
Please note, this herb is HIGHLY TOXIC, and has been reported to cause severe and permanent liver disease which can be fatal.
Recommendation: strongly against (Existing evidence shows that Chaparral is not an effective treatment for chronic pain. In addition, this herb is highly toxic and potentially life threatening.)
Grade of Evidence: low quality of evidence
Red Pepper (Capsaicin):
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (There is insufficient evidence to support claims that red peppers help to treat or prevent chronic pain)
Grade of Evidence: very low quality of evidence
Black Cohosh (cimicifuga Racemosa):
Please note, this management does NOT treat the condition itself. It is proposed only as a weak supportive symptomatic support, and even then, has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (Available evidence does not support claims that Black Cohosh helps to treat symptoms of pain in any way. Studies have yielded mixed results)
Grade of Evidence: moderate quality of evidence
Transcutaneous Electrical Neuromuscular Stimulation:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: weak (There is not enough evidence supporting the role of TENS in chronic pain therapy)
Grade of Evidence: low quality of evidence
Therapeutic Touch:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: weakly in favor (A reliable study demonstrated that this form of therapy helps reduce some types of pain, but more studies are needed)
Grade of Evidence: low quality of evidence
Reiki:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: weakly in favor (some studies show that Reiki may help reduce pain among some patients, but this had no effect on the amount of pain medication they needed to take later)
Grade of Evidence: very low quality of evidence
Reflexology:
Please note, this management does NOT treat the condition itself. It may mildly help with some of the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: weakly in favor (A conrolled study showed that Reflexology may help some people with chronic pain for a maximum of three hours, but shows no effect after that)
Grade of Evidence: low quality of evidence
Polarity Therapy:
Please note, this management does NOT treat the condition itself. It may mildly help with the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (available research does not show that Polarity Therapy might help reduce pain)
Grade of Evidence: low quality of evidence
Osteopathy:
Please note, this management does NOT treat the condition itself. It may mildly help with the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (Available scientific evidence does not support Osteopathy as helpful alone in chronic pain)
Grade of Evidence: low quality of evidence
Neural Therapy:
Please note, this management does NOT treat the condition itself. It may mildly help with the symptoms, and even then has insufficient evidence to back up this claim at present.
Recommendation: no recommendation (no reliable clinical studies have been done to support Neural Therapies role in reducing chronic pain)
Grade of Evidence: very low quality of evidence
Myofascial Release:
Recommendation: weakly in favor (small initial studies show that myofascial release may help in chronic pelvic pain, but there is insufficient evidience for this, and other types of pain)
Grade of Evidence: very low quality of evidence
Massage:
Recommendation: strongly in favor (Some studies have shown that massage therapy can help decrease chronic pain)
Grade of Evidence: low quality of evidence
Low-Level Laser Therapy:
Recommendation: no recommendation (There have been ambiguous results on the few studies done investigating the effect of laser therapy on chronic pain)
Grade of Evidence: very low quality of evidence
Acupuncture:
Recommendation: strongly in favor (There is some evidence that suggest that Acupuncture may decrease the need for pain medication)
Grade of Evidence: low quality of evidence
Qigong:
Recommendation: weakly in favor (One published study found that Qigong may help in reduction of chronic pain)
Grade of Evidence: low quality of evidence
Aromatherapy:
Recommendation: weakly in favor (early trials suggest that Aroma therapy helps patients cope with chronic pain)
Grade of Evidence: low quality of evidence
Creative Art Therapy (Expressive Therapy):
Recomendation: no recommendation (there is no reliable evidence suggesting that creative arts therapy may help manage chronic pain)
Grade of Evidence: very low quality of evidence
Ayurvedic Medicine (Ayurveda):
Recomendation: no recommendation (there is insufficient evidence that suggests that Ayurvedic Medicine may help manage chronic pain)
Grade of Evidence: very low quality of evidence
Curanderismo:
Recommendation: no recommendation (although there are reports from people that Curanderismo may help deal with pain, but there are no reliable studies done yet)
Grade of Evidence: very low quality of evidence
Humor Therapy:
Recommendation: weakly in favor (One study has shown that humor therapy may help increase pain tolerance)
Grade of Evidence: very low quality of evidence
Hypnosis:
Recommendation: strongly in favor (There are many reports that demonstrate that hypnosis helps patients better manage and reduce pain)
Grade of Evidence: low quality of evidence
Image Therapy:
Recommendation: weakly in favor (a review of a number of studies conducted showd that Image Therapy may be helpful in reducing pain)
Grade of Evidence: low quality of evidence
Meditation:
Recommendation: strongly in favor (clinical trials have shown that meditation can help reduce chronic pain)
Grade of Evidence: low quality of evidence
Music Therapy:
Recommendation: strongly in favor (Music therapy has been shown to be effective for short-term management of pain)
Grade of Evidence: low quality of evidence
Native American Healing:
Recommendation: no recommendation (No reliable studies have shown that Native American Healing may help deal with chronic pain)
Grade of Evidence: very low quality of evidence
Naturopathic Medicine:
Recommendation: no recommendation (No reliable studies have shown that Naturopathic Medicine may help to deal with chronic pain)
Grade of Evidence: very low quality of evidence
* www.gradeworkinggroup.org
Summary References
Treatments:
1. Ades T, Alteri R, Gansler T, Yeargin P, "Complete Guide to Complimentary & Alternative Cancer Therapies", American Cancer Society, Atlanta USA, 2009
2. Edible and Medicinal Plants of the West, Gregory L. Tilford, ISBN 0-87842-359-1
3. http://www.hc-sc.gc.ca/ahc-asc/media/advisories-avis/_2005/2005_135-eng.php
4. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/chaparral
5. http://www.nlm.nih.gov/medlineplus/marijuana.html
6. http://nccam.nih.gov/research/extramural/awards/2004/
7. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/marijuana
8. http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms/treatments/complementary--alternative-medicine/marijuana/index.aspx
9. http://www.ncbi.nlm.nih.gov/pubmed/16957511
10. http://www.ncbi.nlm.nih.gov/pubmed/12965981
11. http://www.ncbi.nlm.nih.gov/pubmed/17589370
12. http://mct.aacrjournals.org/content/6/11/2921.long
13. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562334/?tool=pmcentrez
14. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/pau-d-arco
15. David Michael Wood et al. Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data. Critical Care October 2002 Vol 6 No 5
16. Arnold, M.D., Harry L. (1968). Poisonous Plants of Hawaii. Tokyo, Japan: Charles E. Tuttle Co.. p. 20. ISBN 0804804745.
17. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/strychnos-nux-vomica
18. http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/turmeric
19. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-turmeric.html
20. http://nccam.nih.gov/health/turmeric/index.htm
21. http://news.bbc.co.uk/2/hi/health/1668932.stm
22. http://www.mirror.co.uk/news/top-stories/2009/10/28/curry-kills-cancer-cells-and-other-health-benefits-of-the-nations-favourite-dish-115875-21779950/
23. http://clinicaltrials.gov/ct2/results?term=turmeric