Everyone Healthy Library
Sickle Cell Anemia
Also Known As: Sickle Cell Disease
Condition / disease reference page from the Everyone Healthy database.
Connected health information
Explore this condition in a clear order
Condition overview
Attributes
Commonalityis rare
Commonality for Afghanistanis uncommon
Commonality for Central Africais common
Commonality for East Africais common
Commonality for Pakistanis uncommon
Commonality for Southern Indiais uncommon
Commonality for Zimbabweis common
Linked signs and symptoms
23Each sign/symptom opens its own page and links back to related conditions.
- Anaemia (Anemia)
- Blood Flow Reduced (Ischaemia)
- Blood in Urine (Hematuria)
- Breath Shortness (Dyspnoea)
- Erection Pain
- Eye: Vision Impairment
- Fatigue
- Feet Swollen
- Fever (Raised Body Temperature)
- Foot Ulcer (One Only)
- Growth Impairment or Stunted
- Heart or Pulse Rate Raised (Tachycardia)
- Immune Dysfunction
- Pain Abdominal
- Pain Bone
- Pain Joint (Arthralgia)
- Pain: Chest
- Reduced Immune System Function
- Skin Yellowing (Jaundice)
- Skin: Pale, Lack of Colour (Pallid Complexion)
- Thirst
- Urination of Large Volume of Urine (Polyuria)
- Vomiting
Linked drugs / medications
1Medication information is educational only. A doctor or pharmacist should advise whether any medicine is appropriate.
Treatments, therapies and supportive options
2Grouped by treatment type. These are educational database links, not personal treatment recommendations. Evidence labels are shown only where stored in the EH database.
Medical therapy
1Linked diagnostic tests and investigations
39These are pulled from both EH diagnostic-test link tables, including the older large test-link table.
- 2,3 Diphosphoglycerate (2,3-DPG) Concentration
- Acid Phosphatase Concentration
- Bilirubin total concentration
- Blood Uric Acid Concentration Test
- Chloride Concentration (Blood)
- Cholesterol Concentration
- Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Chorionic Villus Sampling (CVS)
- D-Dimer Blood Test
- erythrocyte Sedimentation Rate (ESR)
- Ferritin Concentration
- Fetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Fibrinogen Concentration test
- Folic Acid (Folate) Concentration
- Folic Acid (Folate) Concentration
- Glycosylated Hemoglobin (HbA1c) Concentration
- haptoglobin (Hp) concentration
- Heamatocrit (Hct)
- Hemoglobin (Hb) A2 Concentration
- Hemoglobin (Hb) Concentration
- Hemoglobin S Concentration (Sickle Cell Test)
- Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Mean Corpuscular Hemoglobin (MCH) Weight Test
- Mean Corpuscular Hemoglobin Concentration (MCHC)
- Mean Corpuscular Volume (MCV)
- Oxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Oxygen (PO2)
- Platelet Count
- Potassium Concentration (K, Blood)
- Protein C (PC ANtigen)
- Protein S Concentration
- Red Blood Cell (RBC) Count
- Red Blood Cell Distribution Width (RDW) Test
- Reticulocyte Absolute Count
- Urine Osmolality
- Urine Red Blood Cell Cast Concentration
- Urine Uric Acid Concentration
- Urine Volume
Biological and test markers
39This visual map uses existing EH database links to show biological agents and lab markers reported as increased, decreased, or associated with this condition. These are educational relationships only; test results must be interpreted by a qualified clinician because ranges vary by lab, method, age, sex and clinical context.
Often increased
22- 2,3 Diphosphoglycerate (2,3-DPG)Reference range exampleAdult ( > 16y): 10.5–14 µmol/gLinked diagnostic tests12, 3 Diphosphoglycerate (2
- Abnormal Genetic or Biochemical MarkersReference range exampleAdult ( > 16y), Female: 0–1 Not PresentLinked diagnostic tests1Chorionic Villus Sampling (CVS)
- Acid PhosphataseReference range exampleChild (0 - 16y), Male: 8.7–12.5 units/L; Adult ( > 16y), Male: 2.2–10.4 units/LLinked diagnostic tests1Acid Phosphatase Concentration
- Bilirubin (Unconjugated Fraction)Reference range exampleBirth - 2wks: 0–10 mg/dL; Adult ( > 16y): 0.2–0.75 mg/dLLinked diagnostic tests2Bilirubin Concentration (Neonates, Neonatal Bilirubin)
- Chloride (Blood, Cl)Reference range exampleAdult ( > 16y): 97–106 mEq/L; Birth - 2wks: 94–106 mEq/LLinked diagnostic tests1Chloride Concentration (Blood)
- Cholesterol (Total)Reference range exampleInfant (0 - 1y): 75–180 mg/dL; Adult ( > 16y): 0–190 mg/dLLinked diagnostic tests1Cholesterol Concentration
- D-DimerReference range exampleAdult ( > 16y): 0–240 µg/LLinked diagnostic tests1D-Dimer Blood Test
- FerritinReference range exampleChild (0 - 16y): 7–140 µg/L; Adult ( > 16y), Female: 18–160 µg/LLinked diagnostic tests1Ferritin Concentration
- Fetal Hemoglobin (Hemoglobin F, HbF)Reference range exampleAdult ( > 16y): 0–2.1 %; Birth - 2wks: 56–90 %Linked diagnostic tests1Fetal Hemoglobin (Hemoglobin F, HbF) Concentration
- Hemoglobin (Hb) A2Reference range exampleAdult ( > 16y): 1.5–3.5 %; Birth - 2wks: 0–1.8 %Linked diagnostic tests1Hemoglobin (Hb) A2 Concentration
- Hemoglobin SReference range exampleAll: 0–1 Not PresentLinked diagnostic tests1Hemoglobin S Concentration (Sickle Cell Test)
- Human Placental Lactogen (HPL, Pregnancy Weaks 25 to 30)Reference range exampleAdult ( > 16y), Female: 2,300–6,100 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 31 to 35)Reference range exampleAdult ( > 16y), Female: 3,800–8,800 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (hPL, Pregnancy Weaks 36 to 40)Reference range exampleAdult ( > 16y), Female: 4,900–8,600 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- Human Placental Lactogen (HPL, Pregnancy Weaks 5 to 25)Reference range exampleAdult ( > 16y), Female: 0–4,500 µg/LLinked diagnostic tests1Human Placental Lactogen Concentration (hPL, Chorionic Somatomammotropin)
- PlateletsReference range exampleChild (0 - 16y): 150–450 109/L; Adult ( > 16y): 135–380 109/LLinked diagnostic tests1Platelet Count
- Potassium (K, Blood)AbbreviationKReference range exampleInfant (0 - 1y): 4.1–5.3 mEq/L; Child (0 - 16y): 3.4–4.7 mEq/LLinked diagnostic tests1Potassium Concentration (K, Blood)
- Red Blood Distribution Width (RDW)Reference range exampleAll: 11–14.5 %Linked diagnostic tests1Red Blood Cell Distribution Width (RDW) Test
- ReticulocytesReference range exampleAdult ( > 16y): 24–83 109/L; 0.5–1.5 %Linked diagnostic tests2Reticulocyte Absolute Count, Reticulocyte Count Percent Total RBC
- Uric Acid, BloodReference range exampleAdult ( > 16y), Female: 2.5–7 mg/dL; Adult ( > 16y), Male: 4–8 mg/dLLinked diagnostic tests1Blood Uric Acid Concentration Test
- Urine Red Blood Cell CastsReference range exampleAll: 0–0 Not PresentLinked diagnostic tests1Urine Red Blood Cell Cast Concentration
- Urine Uric AcidReference range exampleAdult ( > 16y): 1.48–4.43 mmol/dayLinked diagnostic tests1Urine Uric Acid Concentration
Often decreased
17- CholinesteraseReference range exampleAll: 6–19 U/mLLinked diagnostic tests1Cholinesterase (Serum Acetylcholinesterase, Pseudocholinesterase)
- Erythrocyte Sedimentation RateReference range exampleAdult ( > 16y), Female: 0–20 mm/Hr; Adult ( > 16y), Male: 0–15 mm/HrLinked diagnostic tests1erythrocyte Sedimentation Rate (ESR)
- FibrinogenReference range exampleAdult ( > 16y): 150–400 mg/dLLinked diagnostic tests1Fibrinogen Concentration test
- Folic Acid (Folate)Reference range exampleInfant (0 - 1y): 14–51 ng/mL; Child (0 - 16y): 5–21 ng/mLLinked diagnostic tests1Folic Acid (Folate) Concentration
- haptoglobin (Hp)Reference range example45–200 mg/dLLinked diagnostic tests1haptoglobin (Hp) concentration
- Hemoglobin (Hb)
- Hemoglobin (Hb)Reference range exampleFemale: 78–100 gm/dL; Male: 76–100 gm/dLLinked diagnostic tests3Hemoglobin (Hb) Concentration, Mean Corpuscular Hemoglobin (MCH) Weight Test
- Oxygen Saturation (Arterial Blood, SaO2)Reference range exampleChild (0 - 16y): 95–100 %; Newborn (0 - 1month): 40–90 %Linked diagnostic tests1Oxygen Saturation Test (Arterial Blood, SaO2)
- Partial Pressure of Arterial Carbon Dioxide (PaCO2)Reference range exampleAll: 35–45 mm HgLinked diagnostic tests1Partial Pressure of Arterial Carbon Dioxide (PCO2, PaCO2)
- Partial Pressure of Arterial Oxygen (PaO2)Reference range exampleChild (0 - 16y): 80–100 mm Hg; Newborn (0 - 1month): 60–70 mm HgLinked diagnostic tests1Partial Pressure of Oxygen (PO2)
- Protein CReference range exampleAdult ( > 16y): 70–150 %Linked diagnostic tests1Protein C (PC ANtigen)
- Protein SReference range exampleAdult ( > 16y), Female: 50–120 %; Adult ( > 16y), Male: 55–120 %Linked diagnostic tests1Protein S Concentration
- RBC MassReference range exampleFemale: 36–48 %; Male: 42–52 %Linked diagnostic tests1Heamatocrit (Hct)
- Red Blood Cell (RBC) VolumeReference range example76–100 fLLinked diagnostic tests1Mean Corpuscular Volume (MCV)
- Red Blood Cells (RBC)Reference range exampleAdult ( > 16y), Female: 3.6–5 106/mm3; Adult ( > 16y), Male: 4.2–5.4 106/mm3Linked diagnostic tests1Red Blood Cell (RBC) Count
- UrineReference range exampleAdult ( > 16y): 4.5–7.5; Child (0 - 16y): 500–1,400 mLLinked diagnostic tests5Urine Colour, Urine Creatinine Concentration
- Urine OsmolalityReference range exampleAdult ( > 16y): 250–950 mOsm/kgLinked diagnostic tests1Urine Osmolality
Other associated markers
0No markers in this group.
Introduction / full article
Sickle Cell Anemia
The main information article for this record is not yet available in the database.