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Acute Febrile Neutrophilic Dermatosis

Also Known As: Sweet’s syndrome, is a condition typified by the sudden, simultaneous onset of fever; increased white blood cell count; and tender, red-to-purple lesions

Condition / disease reference page from the Everyone Healthy database.

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Condition overview

Attributes

Commonalityis rare

Linked signs and symptoms

8

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Linked drugs / medications

1

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Treatments, therapies and supportive options

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Linked diagnostic tests and investigations

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Biological and test markers

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Often decreased

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Other associated markers

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Introduction / full article

Acute Febrile Neutrophilic Dermatosis

ID 344

 

Acute Febrile Neutrophilic Dermatosis

 

Acute febrile neutrophilic dermatosis, also known as Sweet’s syndrome, is a condition typified by the sudden, simultaneous onset of fever; increased white blood cell count; and tender, red-to-purple lesions.

 

Causes

The risk of acute febrile neutrophilic dermatosis is increased considerably for patients with certain pre-existing disorders, including:

·         Acute respiratory disorder;

·         Infection of the gastro-intestinal tract;

·         Autoimmune disorders; or

·         Cancer.

 

Pathophysiology

Acute febrile neutrophilic dermatosis occurs as a reaction to systemic factors, such as infection, inflammation or exposure to particular substances.

 

Symptoms and diagnosis

Aside from the characteristic signs, other symptoms associated with acute febrile neutrophilic dermatosis include:

·         Inflammation membranes surrounding the eye;

·         Joint pain; and

·         Dysfunction of internal organs.

Patients with the condition are usually diagnosed based on inspection of the hallmark lesions. Clinical analysis of a sample of lesioned skin can be used to confirm the diagnosis.

 

Treatment

Drugs can be used effectively to restore bodily temperature, white blood cell count and the condition of the skin to normal.